Future of Genomics

Molecular biology has long held out the promise of transforming medicine from a matter of serendipity to a rational pursuit grounded in a fundamental understanding of the mechanisms of life. Molecular biology has begun to infiltrate the practice of medicine; genomics will hasten the advance. Within 50 years, we expect comprehensive genomics-based health care to be the norm. We will understand the molecular foundation of diseases, be able to prevent them in many cases and design accurate, individualized therapies for illnesses.

In the next decade, genetic tests will routinely predict individual susceptibility to disease. When the genome is completely open to us, such studies will reveal the roles of genes that individually contribute weakly to diseases but interact with other genes and with environmental influences, like diet, infection and prenatal exposures to affect health.

By 2010 to 2020, gene therapy should also become a common treatment, at least for a small set of conditions. Within 20 years, novel drugs will be available that derive from a detailed molecular understanding of common illnesses like diabetes and high blood pressure. The drugs will be designer therapies that target molecules logically and are therefore potent without significant side effects. Drugs like those for cancer will routinely be matched to a patient’s likely response, as predicted by molecular fingerprinting. Diagnoses of many conditions will be much more thorough and specific than now. For example, a patient who learns that he has high cholesterol will also know which genes are responsible, what effect the high cholesterol is likely to have, and what diet and pharmacologic measures will work best for him.

By 2050, many potential diseases will be cured at the molecular level before they arise, though large inequities worldwide in access to these advances will continue to stir tensions. When people become sick, gene therapies and drug therapies will home in on individual genes, as they exist in individual people, making for precise and customized medical treatment. The average life span will reach 90 to 95 years, and a detailed understanding of human aging genes will spur efforts to expand the maximum span of human life.

In Future, the complete DNA sequencing of more and more organisms, including humans, will revolutionize biology and medicine. It is predicted that genomics will answer many important questions, such as how organisms evolved, whether synthetic life will ever be possible, and how to treat a wide range of medical disorders.

If, within a few years, scientists can expect to amass a tidy directory of the gene products—RNA as well as proteins—essential for life, they may well be able to make a new organism from scratch by stringing DNA bases together into an invented genome coding for invented products. If this invented genome crafts a cell around itself and the cell reproduces reliably, the exercise would be the ultimate proof that we understand the basic mechanisms of life.

In the last 50 years, a single gene or a single protein often dominated a biologist’s research. In the next 50 years, researchers will shift to studying integrated functions among many genes, the web of interactions among gene pathways, and how outside influences affect the whole system.

Within 50 years, with all genes identified and all possible cellular interactions and reactions charted, pharmacologists are developing a drug or toxicologists trying to predict whether a substance is poisonous may well turn to computer models of cells to answer their questions.

Being able to model a single cell will be impressive, but to fully understand the life forms we are most familiar with, we’ll plainly have to consider additional levels of complexity. We will have to consider how genes and their products behave in place and time—that is, in different parts of the body and in a body that changes over a lifespan.

So far, developmental biologists have striven to find signals that are universally important in establishing an animal's body plan, the arrangement of its limbs and organs. In time, they will also describe the variations—in gene sequence, perhaps in gene regulation—that generate the striking diversity of forms among different species. By comparing species, we’ll learn how genetic circuits have been modified to carry out distinct programs, so that almost equivalent networks of genes fashion, for example, small furry legs in mice and arms with opposable digits in humans.

In 50 years, we will fill in many details about the history of life, though we may still not understand how the first self-replicating organism came about; we will learn when and how – by inventing, adopting, or adapting genes – various lineages acquired, for example, new sets of biochemical reactions and different body plans. The gene-based perspective of life will have taken hold so deeply among scientists that the basic unit they consider will likely no longer be an organism or a species, but a gene. They will chart which genes have traveled together for how long in which genomes.

Scientists will also address the question that has dogged people since Darwin’s day: What makes us human? What distinguishes us as a species? Undoubtedly, many other questions will arise over the next 50 years. As in any fertile scientific field, the data will fuel new hypotheses. Paradoxically, as it grows in importance, genomics may not even be a common concept in 50 years, as it radiates into many other fields and ultimately becomes absorbed as part of the infrastructure of all biomedicine.

Genetic information and technology will afford great opportunities to improve health and alleviate suffering. But any powerful technology comes with risks, and the more powerful the technology, the greater the risks. In the case of genetics, people of ill will today use genetic arguments to try to justify bigoted views about different racial and ethnic groups. How we will come to terms with the explosion of genetic information remains an open question.
(www.asifjmir.com)

GM Food -- A Boon or Doom

New technologies play an increasing role in food production, and genetically modified foods (GMF) are at the forefront of the changing nature of our food culture. The promise of GMFs seems almost too good to be true. With a human population of more 6 billion, producing higher yielding foods may be more crucial than ever. Genetically modified (GM) crops are now grown in more than 16 countries. In 2002, farmers around the world planted 60 million hectares of land with dozens of varieties of GM crops. The appearance of GMFs in the marketplace of the West has resulted in a firestorm of public debate, scientific discussion, and media coverage. A variety of ecological and human health concerns come with the new advances made possible by GM.
GM is the technique of changing or inserting genes. Genes carry the instructions for all the characteristics that an organism – a living thing – inherits. They are made up of DNA. GM is done either by altering DNA or by introducing genetic material from one organism into another, which can be either a different variety of the same or a different species. For example, genes can be introduced from one plant to another plant, from a plant to an animal, or from an animal to a plant. Transferring genes between plants and animals is a particular area of controversy. Developing countries have special interests, but fairer trade rules would do more to eliminate hunger than GM crops.

GM foods offer a way to quickly improve crop characteristics such as yield, pest resistance, or herbicide tolerance, often to a degree not possible with traditional methods. Further, GM crops can be manipulated to produce completely artificial substances, from the precursors to plastics to consumable vaccines.

By manipulating the genetic code of organisms that provide food sources, they have created new strains of plants and animals capable of growing larger in less time on less suitable soil. From an ecological perspective, adding more food to a starving population promotes reproduction, exacerbating the very condition scientists are trying to solve.

The policymakers of Pakistan ought to see how GM technology can help produce more food and offer medical, social and economic benefits but without attached threats. Some of the many health advantages of GMF include the edible vaccines, which can help curb various diseases in Pakistan. Nutritionally improved crops with a higher content of proteins and vitamins can supplement the nutritional requirements of the lower strata of the population, who cannot afford a non-vegetarian diet. Pulses constitute a major source of protein in Pakistan. However, the presence of raffinose-like sugars can cause digestive problems. The genetically tailored pulses that contain reduced amounts of raffinose and similar sugars can result in enhanced digestibility. GMF that contain sweet proteins like thaumatin will be good for people with diabetes. And GMFs that have greater iron content can be especially beneficial for Pakistani women, as they are susceptible to anemia.

GM crops can result in enhanced agricultural productivity with lower inputs in terms of plant protection strategies and fertilizer applications, raise the per capita income and, hence, the living standard. Further, the availability of better quality nutrition at affordable costs can also improve the general health of the population, which in turn will raise national productivity.
Contrary to the natty payback, many leading scientists admit that GM is unpredictable, unstable, and potentially dangerous because of the consequences. GMF raises the possibility of human health, environmental, and economic problems, including unanticipated allergic responses to novel substances in foods, the spread of pest resistance or herbicide tolerance to wild plants, inadvertent toxicity to benign wildlife, and increasing control of agriculture by biotechnology corporations.

In Pakistan it will be a tragedy if the multinational corporations pushing genetically engineered crops gain control over crops and seeds. Although the corporations claim biotechnology is needed to feed the world, this is a myth. There is already more than enough food to feed everyone; poverty and inadequate allocation of resources are the major hurdles. According to a FAO report, the world can produce enough food to meet global demand in the year 2030 without the use of GM crops.

Meanwhile, organic farmers are among those most threatened by GMF. One reason is because cultivation of genetically engineered crops on neighboring farms can contaminate their crops via pollen drift. No genetically engineered materials should be used in organic products. Thus, a grower may be unable to sell his or her crop as organic if it has been contaminated
Ultimately, it is the consumer--and all Earth's inhabitants--who have the most to lose in the long run. Because little thought is being given to the consequences of what GM crops will do to the environment and to biodiversity, Earth's ecosystem could be turned upside down. There will be no way to undo the damage or recall new organisms that have been unleashed.
Large seed companies are likely to make large profits from GM crop seeds. This will be exacerbated if they make crops that produce sterile seeds, which cannot be replanted the following year. Consumers and small farmers who are forced to buy seed year after year will lose.

Pakistan needs to adopt a harmonized, uniform and transparent procedure for safety assessment of GMF. Coordinated and comprehensive labeling requirements for GMF should also be prepared with the aim of providing the consumer with a real choice.

Pakistan has a national food poverty rate of 33% and 40% of children under the age of five are underweight, 50% are stunted, and 9% are wasted. The GMF has the capability of overcoming these problems. Its dubious impact, nevertheless, compels us to seriously consider all pros and cons before the risks involved in GMF take the nation by surprise. (www.asifjmir.com).

Save Mother Earth

It is true to say that we live on a planet that is undergoing rapid changes due to the increases in population and industrial development. It is easy to feel environmental concerns, but they must be taken into account when considering our future.

It is now a proven fact that since the industrial revolution the amount of carbon dioxide in the atmosphere has increased significantly. As levels of this gas and other greenhouse gases also recently building up effect the way heat is distributed, it is predicted that there will be an increase in global temperature. It is certain that global population growth will continue for some considerable time to come. A larger global population will put expanding demands on global resources of food, water and energy and will accelerate climate and environmental deterioration.

The level of air pollution in Pakistan's two largest cities, Karachi and Lahore, is estimated to be 20 times higher than World Health Organization standards, and continuing to rise. The situation is depressing by reason of futile preparation and inept execution. Good and not so good regulations have never been enforced forcefully. In addition, enforcement does not imply effectiveness, and even if regulations were strictly enforced, many industries would be unable to comply. In 1996, only 3% of industries were able to pass the test for compliance.

For lacking combined effluent treatment facility, the wastewater is being allowed to flow into the nearest streams and causing pollution. The sub-soil waters of textile centers are highly saline and as such are unsuitable for producing high quality finished textile products. The saline or brackish sub-soil water is unfit for human consumption and also unsuitable for most of the industrial uses.

Air pollution has also become a major problem in most cities. There are no controls on vehicular emissions, which account for 90 percent of pollutants. The average Pakistani vehicle emits twenty-five times as much carbon monoxide, twenty times as many hydrocarbons, and more than three and one-half times as much nitrous oxide in grams per kilometer as the average vehicle in the United States.

Pakistan’s Perspective Plan (1988-2003) and previous five-year plans do not mention sustainable development strategies. There have also been no overarching policies focused on sustainable development and conservation. All our programs focus on reaching self-reliance in food production, meeting energy demands, and containing the high rate of population growth. Sorry to say, no priority has been accorded for curtailing pollution or other environmental hazards.

Consequently, deforestation has contributed directly to the severity of the flooding problem faced by the nation in the early 1990s. No solution has been found for the solid and liquid excreta that are the major source of water pollution in the country and the cause of widespread waterborne diseases. Because only just over half of urban residents have access to sanitation, the remaining urban excreta continue to be deposited in farms or on roadsides, into waterways, or incorporated into solid waste. Thus the vegetables grown from such wastewater have serious bacteriological contamination. Gastroenteritis, widely considered in medical circles to be the leading cause of death in Pakistan, is transmitted through waterborne pollutants.

Transportation contributes to four of the six criteria pollutants: ozone, carbon monoxide, particulate matter, and nitrogen dioxide. Pakistan’s transportation planning (if it all there is any) must take into account the impacts on both the natural and human environments. Transportation projects should closely see how they might impact the community, the natural environment, and our health and welfare.

In crowded streets filled with buses, trucks, automobiles, and motorcycles, often honk senselessly. Traffic noise should be reduced through a program of shared responsibility. Thus, provincial and local governments should practice compatible land use planning and control in the vicinity of roads. Local governments should use their power to regulate land development in such a way that noise-sensitive land uses are either prohibited from being located adjacent to a road, or that the developments are planned, designed, and constructed in such a way that noise impacts are minimized.

The EPA should also promote bicycle and pedestrian transportation accessibility, use, and safety. A long-range plan is needed to provide the development and integrated management and operation of transportation systems and facilities, including pedestrian walkways and bicycle transportation facilities.

Protecting public health, as well as preserving Pakistan's natural wonders, has made environmental protection increasingly important. Environmental issues attach more significance because under provisions of a World Trade Organization (WTO) agreement, Pakistan will have difficulty after 2005 exporting products from industries without adequate environmental safeguards.

Because Pakistan, along with other developing countries, has argued that it needs to be free of emission ceilings in order to develop its economy, the country has not taken on any emission reduction commitments under the United Nations Framework Convention on Climate Change, nor is Pakistan a signatory to the Kyoto Protocol.

There are many things we can do to help reduce damage to our local, and therefore global, environment. An obvious one is attempting to reduce unnecessary consumption of products and power. Good insulation, lower heating thermostat settings, turning off appliances, solar heating and so on, as well as sensible use of water could be considered. Care can be taken to try to purchase goods which use less packaging waste and if possible less transportation. Where meat eaters should of course be concerned about animal welfare, vegetarians should be careful about the total amount of energy used in the production and transport of their food, which in some cases can threaten the effective environmental benefit of such a lifestyle.

The only course of action for us must surely be to make our individual effort to care for our world and encourage others, especially the young, to do the same. By working together at a local, national and international level it should be possible for our Mother-earth to have a viable future. (www.asifjmir.com)

Education: Changing the Tunes

The state of education in Pakistan is depressing. Today we cannot compete even with third-rate countries in standard indicators of academic achievement. Weak curricula and discipline have guaranteed educational failure for tens of millions of our children. The nation should therefore look to itself and conclude that something must be done.

We are perhaps after increasing the number of educational institutions and ignoring the future of education, which is about the demise of the classroom-based teacher, and an information technology lead revolution in schools, colleges and universities.

For meeting our future economic needs, we must not lose sight of the fact that education is a process, not a commodity. It benefits the individual, and society as a whole, in all sorts of ways that are not necessarily quantifiable in terms of our national balance sheet.

Developed societies use teachers not as objects, but engines of education reform. Contrarily, our policymakers use them not as engines but tail cabins. Thus teachers are not involved in policy process for education. We need to see teachers as custodians of intellectual and cultural tradition, not servants of a government mission.

The report of the Pakistan Task Force on Improvement of Higher Education estimates that 18 million people are in the age between 17 to 23 years, eligible for tertiary education. Out of them, only 475,000 (or about 2.6%) are actually enrolled in higher education institutions. This proportion is among the lowest in the world: India (in 1990) had a tertiary enrolment ratio of 6.2%, while Iran (in 1994) had 12.7%. This is pathetic. It asks for direction and relevancy of higher education research.

Higher education in Turkey is worth talking about. The average annual growth rate of students in higher education in Turkey during the period 1980-85 was one of the highest in the world: 14.1% as compared to 7.8%in Canada, 5.0% in the UK, 1.4% in Italy, 0.2% in the US, -0.2% in Hungary, and -5.3% in Poland. The number of students enrolled in engineering is high: 18.33 %of the total enrollment as compared to 8.20 %in Italy, 7.90 %in Austria, and 3.29 %in France. In the area of higher education, can we seek some route from Turkey’s experience?

People need more education than ever before, and distance learning—connecting cable and classroom—offers a way to meet that need. Internet delivers course material to homes or offices. Discussions, assignments and exams are being done online. Some of these are courses offered by traditional universities, of which the University of Phoenix is the largest, some by accredited virtual universities with no on-campus instruction and some by unaccredited institutions. For many students, however, especially those with full-time jobs or those far from campuses, the savings in commuting and the flexibility to make their own schedules make the total cost less than that of alternatives.

The concept of virtual university is not a bad idea, which Pakistan must adopt at a large scale. It can distribute cheap Internet access and classroom content to modular learning kiosks in several thousand villages. Distributing several thousand simple, mass-produced kiosks might be less expensive than creating even one old-style university campus.

Pakistan has recently allocated resources greater than ever before. Nonetheless, it didn’t fully utilize even what paltry had been allocated earlier. Owing to intricate bureaucratic labyrinth drawing money is like pulling teeth. Consequently, the trend of spending in Pakistan is far less than the allocated money in all eight plans. There are around twenty-two steps to draw the allocated money. For survival in the new world, Pakistan has got to adopt new ways of governance.

South Korea offers an interesting paradigm in modern history. Most observers agree that it's spectacular progress in modernization and economic growth since the Korean War is largely attributed to the willingness of individuals to invest a large amount of resources in education.

Korea's liberation from Japan marked a turning point in the history of education. As the country underwent a transition from totalitarian rule to democracy, a primary concern was to provide everybody with equal educational opportunities. The period from 1945 to 1970 witnessed a dramatic expansion of education. In spite of the widespread destruction and economic suffering brought about by the Korean War (1950-1953), Korea succeeded in virtually eliminating illiteracy. Such a rapid expansion was naturally accompanied by problems, the most serious being deterioration in the quality of education. As the 1960s drew to a close, Korea's educators turned their attention to these problems and several projects were launched to improve the curricula and the methods of instruction

Although only primary school was compulsory in Korea, proportion of age-groups of children and young people enrolled in primary, secondary, and tertiary level schools were equivalent to those found in industrialized countries, including Japan. The percentage of students going on to optional middle school the same year was more than 99 percent. Approximately 34 percent, one of the world's highest rates of secondary-school graduates attended institutions of higher education in 1987, a rate similar to Japan's (about 30 percent) and exceeding Britain's (20 percent). The number of students in higher education had risen from 100,000 in 1960 to 1.3 million in 1987, and the proportion of college-age students in higher education institutions was second only to the United States.

Can Pakistan learn from the South Korean experience that explains the important role of education in its evolution from one of the world's poorest countries 50 years ago eating dogs to fuel the stomach, into a major economic success today?

A serious look at the state of the world raises a question regarding the thought process of Pakistan’s decision makers. Years of traditional education are no guarantee of a mature intellect. Entrenched mentalities need to change or institutions will continue to play the same old games and repeat the same old tunes. Schools of the future have an opportunity and responsibility to change the tune. (www.asifjmir.com)

The Demographic Coop up

As we approach the future, new demographic criteria are needed. The world is dividing largely into countries where population growth is slow or nonexistent and where living conditions are improving and those where population growth is rapid and living conditions are deteriorating or in imminent danger of doing so. Pakistan is in second group in its fifth decade of rapid population growth. Not only has it failed to complete the demographic transition, but the deteriorating relationship between people and ecological support systems is lowering living standards.

Pakistan’s population now just around 150 million is projected to reach 330 million before it stops growing toward the middle of this century. It is more than double before stabilizing. This means combination of soil erosion and ill-conceived agricultural policies will lead to poverty increase. Population projections in Pakistan where life support systems are already trifling can only be described as projections of disaster.

The wide variations in projected population growth suggest that a demographically divided world is likely to become more deeply divided along economic lines as well. Unless this relationship between rapidly multiplying populations and their life-support systems can be stabilized, development policies, however imaginative, are likely to fail.

Throughout most of human history, the general increase in human numbers was accompanied by a slow expansion of the cropland area. As populations grew, land pressures built, the landless migrated to big cities. This is the cause of urbanization in Karachi, Lahore and other big cities. The cropland area might have grown but not nearly as fast as population. Thus the result is growing rural landlessness—lack of access to land either through ownership or tenancy. Though fueled by population growth, rural landlessness is exacerbated by the concentration of land ownership.

The growth in landlessness can be curbed or even reversed by initiating land reform. To check the growth in landlessness is to slow population growth through effective family planning. Land reform can reduce landlessness in the short run, but in the long run only population stabilization will work.

Numerous linkages exist between population growth and conflict, both within and among societies. Conflict arises when growing populations compete for a static or shrinking resource base. Inequitable distribution of resources—whether of income, land or water—complicates the relationship. Increased competition and conflict fray the social fabric that helps maintain social harmony.

For Pakistan, the global economic slowdown has come just as record numbers of young people are entering the job market. The specter of growing numbers of restless unemployed youngsters in the street does not convey an image of social tranquility. Unemployed youths roaming the streets of Pakistan where half the population under 18 years of age, with no prospect of job formation, hungry, and looking to irregular leaders to lead them in new and as yet unpredictable movements—there is little question that even more political explosions are on the immediate horizon.

In Pakistan the demographic trap is becoming the grim alternative to completing the demographic transition. The high fertility, low mortality stage cannot continue for long. By now Pakistan should have put together a combination of economic policies and family planning programs that reduce birth rates and sustain gains in living standards. If it failed further, continuing rapid population growth eventually overwhelm natural support systems, and environmental deterioration starts to reduce per capita food production and income.

Pakistan perhaps does not know when it is crossing the various biological thresholds that eventually lead to economic decline. One of the first economic indications that pressure on the land is becoming excessive is declining grain production per person. In earlier agricultural societies, population increases were simply matched by those in cultivated area. Grain output per person was stable. When population growth is rapid and there is no new land to plow, expanding the use of modern inputs fast enough to offset the effects of land degradation and to raise land productivity in tandem with population growth is not easy. It comes as no surprise that per capita grain production is declining.

When this happens it is a matter of time until the government translates into a decline in per capita income, and into the need for food imports. Rising food imports contribute to growing external debt. If external debt rises fast enough, it will eventually cross a debt-servicing threshold, beyond which Pakistan can no longer pay all the interest. At this point lenders insist that the unpaid interest be added to the principal, expanding the debt further.

The demographic trap is not easily recognized because it involves the interaction of population, environmental, and economic trends, which are monitored by various ministries and departments. And managers frequently fail to distinguish between triggering events and underlying instability in the population-environment relationship.

Lacking a ground in ecology and an understanding of carrying capacity, all too many economic planners and population policymakers have failed to distinguish between the need to slow population growth and the need to halt it. If societal demands are far below the sustainable yield of natural systems, then slowing population growth is sufficient. But when they have passed these thresholds, the failure to halt population growth leads to deterioration of support systems.

Other countries are moving into uncharted territory in the population-environment-resources relationship. Pakistan cannot remain much longer in the middle stage of the demographic transition. Either it must forge ahead with all the energies at its disposal, perhaps even on an emergency basis, to slow and halt population growth, or it will slide into the demographic trap. At present the government is faced with the monumental task of trying to reduce birth rates as living conditions deteriorate a challenge that may require some new approaches. If it failed, economic deterioration could eventually lead to social disintegration of the sort that undermined earlier civilizations when population demands became unsustainable. (www.asifjmir.com)

Water: A Dehydrated Future

Water resources are declining and different UN reports confirm that serious shortages are occurring soon. Thus we see a future when there will be no or less drinking water.

Access to water is a human right. Current declarations on human rights include basic water needs sufficiently. Basic water rights focus only on water for domestic use, and speak only of amounts of the order of 30-50 liters per person per day. Nonetheless, for many poor people, access to water for productive purposes is a crucial basic need as well. This is because water is a key factor of production in agriculture and for most other forms of economic activity that are vital to the livelihoods and opportunities of the poor.

Some question the wisdom of providing water of drinking quality at great expense, only to have a large share flushed down toilets, to carry waste, where after it is cleaned again for the few that can afford this costly practice. Opinions differ: some water experts advocate ecological sanitation, others dry toilets, some people argue that only bottled water should be of drinking quality and piped water quality should be limited to fit all other use made of it. All these alternative approaches deserve more attention.

Water infrastructure of Pakistan is turning into archaic. Reservoirs are silting up irrigation networks and turning disrepair. Groundwater levels are falling in important aquifers that have contributed substantially to food security in recent years by providing water-on-demand to millions of farmers that tapped them using tube-wells to grow their crops. This situation has impacted adversely causing a serious scarcity of water resources. This scarcity has hit the poor and vulnerable-first and hardest.

Pakistan’s per capita water availability in 1951 was 5,650 which has fallen to around 1,200 cubic meters 1,200 and with current population growth rate, it will be reduced to 1,000 cubic meters by the year 2012. So the hard reality that we as people faced today is that Pakistan in the past fifty years has turned into a water-scarce from a water-sufficient country and the situation continues to go downhill. This is the specimen of a mismanaged case.

Pakistan is the victim of repeated wrong planning of its land and water resources to produce food. All this is due to the pathetic and inert attitude of the technocrats, bureaucrats, politicians and the government as no national policy on water development was framed.

Large-scale development of river and groundwater resources is less acceptable today, for environmental reasons. It is also less cost effective than it was in the 1960-1990 period, when the large majority of the world's 45,000 large dams were built.

Water can be distributed through government institutions or the market. Privatization of water service provision, however, does not imply privatization of water resources. Water is a public good, which should be treated as an economic good where it is used for economic purposes. The public-private sector role nevertheless does not imply the role of multinational companies but the role and significance of the small-scale private sector.

In agriculture, private farmers have been largely responsible for the major investments in groundwater development. This groundwater use has contributed significantly to food production and the creation of wealth in rural areas. But government has failed to elaborate rules and mechanism ensuring that groundwater is used in a way that minimizes the risks of over-use and protects groundwater quality.

Increasing the efficiency in irrigated agriculture can result in large water savings. The UN Secretary General once rightly uttered: We need a Blue Revolution in agriculture that focuses on increasing productivity per unit of water. Indeed, at the farm level, the focus on water productivity in physical terms, crop output per unit of water, is a necessary and useful framework. Likewise, appropriate soil fertility and plant nutrition management can be a way to achieve more crops per unit of water. Water productivity at the basin level must be defined to include crop, livestock and fishery yields, wider ecosystem services and social impacts such as health, together with the systems of resource governance that ensure equitable distribution of these benefits.

For sustainable development, it is clear that better water management should be a means to reduce poverty. Strategies to address water-poverty relationships need to improve the different capabilities of the poor in their battle against poverty. These strategies also need to address the pervasive gender issues in water. Those affected by water problems are too often women, while those deciding on solutions tend to be men. Building gender-equitable capabilities of the poor to manage their water resources should also be at the heart of capacity building in the water sector.

The Provinces should formulate a water supply master plan and continuous planning process to estimate demand for drinking water and identify alternative ways of meeting that demand.

They should also establish and allocate resources to local governments for the preparation of provincial-mandated water supply plans. The Provinces should also enact legislation requiring local governments to formulate and administer comprehensive watershed protection programs in designated future water supply watersheds.

A system needs also to be evolved to promote the adoption of best management practices to minimize agricultural erosion in designated future water supply watersheds by funding and extending existing state cost-sharing programs to those watersheds and by targeting federal, state, and local technical assistance programs to them. A framework also has to be in place to increase technical assistance to local governments to help them prepare and administer watershed protection programs for designated future drinking water sources.

In evaluating alternatives for conjunctive use, water managers should also view ground water as more than a supplement to surface supplies. In particular, managers should assess the value of ground water in optimizing storage capacity, enhancing transmission capabilities, and improving water quality of the system. (www.asifjmir.com)

Cultural Raid by McWorld

Today’s global economy has a tendency to insulate consumers from the various negative impacts of their purchases by stretching the distance between different phases of a product’s lifecycle—from raw material extraction to processing, use, and disposal. Yet at the same time, social challenges accompanying economic globalization call for innovative forms of political mobilization across international borders. Shifting to more sustainable patterns of consumption and production worldwide will require pursuing new ground rules in order to forge a global economy based on protecting cultural values.

What we see is the onrush of the economic, technological, and ecological forces mesmerizing peoples everywhere with fast music, fast computers, and fast food—one McWorld tied together by communications, information, entertainment, commerce and especially the culture.

Today, the global spread of McWorld is rapidly bringing the consumer society of USA to the rest of the planet. The globalization of the consumer economy is closely linked with the general economic boom and growth in the movement of goods, services, and money across international borders, which accelerated during the 1990s.

McDonald’s operates 30,000 restaurants in 119 countries and serves 46 million customers each day. Its total revenue was $15.4 billion in 2002. On opening day in Kuwait City, the line for the McDonald’s drive-through was over 10 kilometers long. McDonald's has also spread expeditiously across Pakistan in major cities. Strangely, there is no McDonald’s outlet in Peshawar and Quetta. McDonald’s costs the same in Pakistan as in the US, and given the per capita GDP disparity between the two countries, it is the cheapest food in one country, while being one of the most expensive in the other.

Pizza Hut also operates a chain of outlets in Pakistan and planning further to invest approximately 1 billion rupees in expansion. The money is being used to open 20 new outlets.

Coca-Cola sells more than 300 drink brands in over 200 countries. More than 70 percent of the corporation’s income originates outside of the United States, and its net revenues reached $19.6 billion in 2002.

Meanwhile, corporate strategies focused on boosting consumer demand in Pakistan have lead to increases in purchases of all manner of goods, from cars and televisions to paper and fast food. While it is ethically problematic to suggest that developing countries are not entitled to have the same options for material consumption that have long been taken for granted by western consumers, the global adoption of industrial country–style consumption patterns would place unbearable strains on local cultures.

The 1990s saw the emergence of many important international agreements and commitments embracing the need to transform unsustainable patterns of consumption and production. Agenda 21, the action plan that emerged from the 1992 Earth Summit in Rio de Janeiro, called on international institutions and national governments to promote greater energy and resource efficiency, minimize waste generation, encourage environmentally sound purchasing, and shift toward pricing systems that incorporate hidden environmental costs.

The UN Commission on Sustainable Development has provided a useful annual venue for governments and others to discuss consumption and production issues. The deliberations have produced little concrete action though. There is no voice raised for conservation of social values.

At the 2002 World Summit on Sustainable Development in Johannesburg, South Africa, governments agreed to develop a 10-year framework of programs to accelerate the shift toward sustainable consumption and production. These include offering a better range of products and services to consumers, providing more information about the health and safety of various products, and establishing programs of capacity building and technology transfer to help share these gains with developing countries. The World Summit also generated more than 230 partnership agreements among diverse stakeholders.

The Organization for Economic Co-operation and Development has sponsored a series of meetings and papers aimed at encouraging governments to implement innovative sustainable consumption and production policies.

In all these forums, apart from consumption and production, no emphasis is laid on the issue of social influence. Unfortunately, the limited gains made since 1992 in shifting toward more-sustainable patterns of consumption and production have been largely overwhelmed by the continued global growth of the consumer society. The controversial lifestyle issues continue to haunt.

The breakdown of WTO negotiations in Cancún in September 2003 provided reform-minded governments and activists with an opportunity to push for bringing future trade negotiations into better balance with sustainable development concerns. The way forward, nevertheless, is not yet clear.

Several new initiatives have emerged in the corporate and financial sectors, including the United Nations’ Global Compact, which calls on participating companies to integrate nine core values related to human rights, labor standards, and environmental protection into their operations, and the Equator Principles, which call on leading banks to manage environmental and social risks in their lending operations.

The international trade negotiations can provide opportunities to push for policy reforms needed to promote more-sustainable consumption and production. All the same, WTO rules and negotiations can also be used to protect cultures and social taboos of the host countries of MNCs.

Brands like McDonald’s, Pizza Hut, Pepsi and Coca-Cola are not just cultural aggression but also an expression of power; once America lost its power these will go. It is nonetheless impossible to filter culture. In the past we hated the British raj but gradually adopted its symbols. Today we hate America and don’t want to adopt what we think is its culture. Pakistan must save its own culture to counter the onslaught. There is a need for reform in our culture, but this should not be obfuscated through this hatred or that. The only answer to the American cultural onslaught is the protection of Pakistan’s own culture. (www.asifjmir.com)